Seretide Diskus: Clinical Use, and Posology

seretide diskus asthma

Seretide Diskus refers to medicine that functions as a long-acting bronchodilator.

Seretide contains Salmeterol and Fluticasone Propionate as active ingredients.

Salmeterol is a beta 2-agonist (molecules that bind to specific receptors within a cell to produce a biological response) that helps to deal with asthma and some respiratory conditions.

Fluticasone Propionate is a glucocorticoid (a type of corticosteroids which helps to fight inflammation and aids the immune system) that allows controlling the symptoms of allergic and non-allergic rhinitis.

People often use this medication to treat issues like shortness of breath, lung diseases, bronchospasm, rhinitis, asthma, etc.

It’s available in several countries such as Colombia, Brazil, Romania, Israel, and many others.

Clinical Use

Medical experts recommend the use of Seretide in cases of asthma where they can’t control their patients’ condition by using commonly inhaled corticosteroids.

A beta 2-agonist may be the best medication for more severe diseases, but in some cases, doctors can choose to use Seretide even when the patients’ symptoms get alleviated by conventional means.

When it comes to other respiratory conditions such as the Chronic Obstructive Pulmonary Disease (COPD), medical experts tend to use.

They resort to this medication especially when a patient suffering from COPD also a Forced Expiratory Volume (FEV1) below 60%.

FEV is the measure of the maximum amount of air that can get expelled in a specific number of seconds during a forced breath.


The route of administration for Seretide Diskus is by inhalation use.

Doctors must instruct their patients that they should use Seretide Diskus daily for optimum benefit, even when such patients are asymptomatic.

Medical experts often advise reassessing patients regularly, to gauge the strength of the medication they’re getting and make sure it remains optimal until no longer needed.

Healthcare providers should figure the lowest dose needed to control the symptoms effectively.

After the patient spends a period inhaling the Seretide combination twice daily, the next step would be including a test of inhaled corticosteroid alone.

If doctors conclude that their patient still requires a beta 2-agonist, then they can prescribe the use of Seretide Diskus once daily if considered adequate for that particular case to control the disease.

When patients have a history of nocturnal symptoms, medical experts would recommend them to receive their dose at night.

If it is the other way around, the person under treatment having a history of daytime symptoms, then they should receive their dose in the morning.

Doctors will decide the best way to proceed depending on the severity of each case.

Recommended Doses

The dosage of salmeterol and fluticasone propionate each patient should get will depend on some specific factors.

For example, if doctors need to treat people that have asthma, they should consider their age before prescribing a dosage.

In the case of adults and teenagers from 12 years and up, they should take one inhalation of 50 micrograms of salmeterol, and anything from 100 to 500 micrograms of fluticasone propionate, twice per day.

Medical experts should determine the amount of fluticasone propionate needed for each particular case.

Doctors may consider a short-term trial of Seretide as initial maintenance therapy when dealing with adults or adolescents who have moderate persistent asthma.

Such cases usually feature patients displaying daily symptoms and severe airflow limitation.

For these people, medical experts recommend an initial dose of one inhalation of 50 micrograms salmeterol and 100 micrograms fluticasone propionate twice each day.

Once they get asthma under control, doctors will have to review or consider whether patients should step down to an inhaled corticosteroid alone.

Medical experts uphold the norm of establishing an appropriate dosage of inhaled corticosteroid for people who have severe asthma before resorting to the Seretide combination.

When it comes to kids with age ranging from 4 to 11 years old, the recommended dosage is one inhalation of 50 micrograms salmeterol and 100 micrograms fluticasone propionate twice each day.

That’s the maximum amount of Seretide Diskus allowed for children is 100 microgram twice each day.

In cases of patients with COPD, medical experts recommend a dosage of one inhalation of 50 micrograms salmeterol and one of 500 micrograms fluticasone propionate twice per day.

There is no need to make adjustments to the dosage for older adults, or patients with renal impairment.

However, there is no information available about the potential effects on patients with hepatic impairment.